Category Archives: Stories of Hope

Stories

Guidance leads to empowerment

Mohammed Alraidi and his wife have long been the greatest supporters of their son who was born with Down syndrome. Always on the lookout for ways to improve their son’s reality and life experiences, they came across Ta’alouf, Al Jalila Foundation’s flagship program that equips parents with the best possible tools to nurture children of determination.

Enrolling in Ta’alouf Parents Training, they eagerly absorbed the knowledge delivered in the course and began implementing it in the family’s daily life. Upon completing the program, Mohammed Alraidi received the certificate with great joy and appreciation for the invaluable knowledge.

“We are so grateful to Al Jalila Foundation and Zayed Higher Organisation for People of Determination for delivering this special educational program taught by passionate instructors to empower children of determination. We have learned so much and leave prepared with better skills to interact with, educate and empower our son. Our son shines in his own way and we hope to inspire other parents with special children to nurture these strengths.”

The Alraidi family moves forward as a positive example encouraging their son’s integration into all areas of society, championing him to participate in hobbies that spark his interest and guiding him to be confident, independent and empowered.

Knocking on the door of hope

It was the beginning of summer 2019 when 6-year-old Vinit Vasandani was devastatingly diagnosed with acute blood cancer (leukemia). The specialists at Dubai Hospital began treatment immediately. However, the family’s medical insurance had reached its annual limit by August. More funds were needed to complete Vinit’s medical plan and his father, Anil, was steadfast in his commitment to provide the best possible treatment for his son.

Undeterred by circumstance, Anil reached out to various channels for support and when the case arrived at Al Jalila Foundation’s door he found the much needed assistance to facilitate the continued treatment.

“As a parent your greatest wish is that your children are healthy and happy. We were heartbroken to learn of our son’s illness, but knowing that Vinit is supported with the greatest care is the ultimate gift for our family.”

Today, Vinit’s treatment continues with positive progress bringing him a step closer every day to a full recovery.

In addition to offering treatment to young patients, Al Jalila Foundation focuses on medical research as it is only through research that illnesses like leukemia are able to be treated successfully today.

Exploring the mysteries of disease

Dr Bashair Mussa from University of Sharjah (College of Medicine) is a cutting-edge researcher leading a study, with the support of Al Jalila Foundation seed grant, investigating the role of FOS and BECLIN1-inducing autophagy in pathogenesis of hypoglycemia-associated autonomic failure (HAAF) in diabetes.

HAAF is a serious complication of diabetes which is associated with unawareness of hypoglycemia (low levels of blood glucose) in patients with diabetes. The main cause of this condition is the absence of physiological homeostatic counter-regulatory mechanisms that are controlled by the hypothalamus (a critical region within the brain).

FOS is a sensitive marker of neuronal activity in the hypothalamus which possesses significant responses to hypoglycemia. Expression of autophagic adaptor proteins such as BECLIN 1, is associated with cognitive dysfunction in diabetes.  It has been suggested that FOS mediates the regulatory effect of BECLIN1 on autophagic processes in the brain.

This project aims to identify the role of FOS and BECLIN 1 in the pathogenesis of HAAF and to profile the involvement of autophagic markers in HAAF.

Identification of novel biomarkers for early detection of HAAF will help patients with diabetes to prevent hypoglycemic episodes, to improve their quality of life and to preserve their cognitive functions.

Walking into a new beginning

Callum was born with an abnormality of his left leg that requires an ortho-prosthesis to enable him to walk and move around independently which must be consistently refitted as he grows.

Callum’s parents have always endeavoured to do everything they can to make sure their son is completely mobile enjoying an active life like other young children.

By the age of 6, Callum had already been fitted with multiple prostheses, however, the expense began to weigh heavily on the family. Not knowing how they were going to be able to provide their son’s next artificial limb, Callum’s parents reached out to Al Jalila Foundation and to their delight, their son was able to receive the much-needed support for his growing body.

“We are forever grateful to Al Jalila Foundation for giving Callum the greatest gift and most importantly for assuring my family that we are not alone in this journey with our son. Thank you very much for making a difference to our lives!”

It is with gratitude to the support from our generous donors that Callum is able to enjoy his days running around the playground with his friends at school.

Click here to see more children whose lives have been transformed.

Emirati doctor inspires students

As a promising Emirati student, Dr Mohamed Jamal dreamt of becoming a dentist and leading ground-breaking research to improve lives.

His journey began at Ajman University where he gained a Doctorate of Dental Surgery in 2005; he then continued to Boston University Institute for Dental Research and Education in Dubai where he obtained a CAGS and MSD in Endodontics in 2011 and received recognition for his outstanding work to isolate dental pulp stem cells for the first time in UAE.

A prestigious scholarship from Al Jalila Foundation allowed Dr Mohamed to obtain his PhD in 2017 from Boston University (BU) in USA. During the scholarship his work gained ‘Best Research Award’ from BU and the American Association of Endodontics (AAE). He also received the ‘Young Emirati Researchers Prize’ from the UAE Ministry of Higher Education and Scientific Research.

“Al Jalila Foundation scholarship opened the door for me to explore science beyond what I imagined. It was a lifetime opportunity and I am thankful for it.”

An Assistant Professor of Endodontics at MBRU and member of the Scientific Advisory Board of the Journal of Endodontics, Dr Mohamed Jamal hopes to contribute to the vision of moving towards a knowledge-based economy and developing top notch research themes in the Emirates.

Early detection saves lives

It had been less than a year since Dubai resident, Sirine Fadoul, had done her annual wellness check which included a breast ultrasound when she detected a very small lump.

As a young, healthy and fit woman with no history of the disease in her family, nothing suggested cancer but she took action and went to get checked quickly. To her shock, the doctor confirmed that she had stage one breast cancer. Although the cancerous tumor was discovered early Sirine still underwent two surgeries including a complete mastectomy, dozens of scans, tests and biopsies and the much-dreaded chemotherapy.

Now 1-year cancer-free, Sirine is unstoppable in her advocacy of the importance of early detection to not only save lives but to make the challenge ‘easier’.

Throughout #PINKtober Brest Friends member, Sirine has been instrumental in supporting Al Jalila Foundation by tirelessly conducting talks at schools, government entities and corporates highlighting the importance of awareness, helping others and investing in local medical research.

Sirine has a great network of friends and knows firsthand that “A strong support system in the way of friends and family and groups such as Brest Friends are invaluable to recovery.”

Watch Sirine’s Story of Hope here.

Zain is given a chance at life

Still in his mother’s womb doctors detected a serious problem with Zain’s growing heart. Zain’s parents anticipated his welcome with a mixture of joy and anxiety unsure of what lay ahead as there was no choice but to wait until his arrival to discover how severe the situation was.

Unfortunately, upon his birth it was confirmed that Zain had a congenital heart defect, Tetralogy of Fallot, and his survival was dependent on critical open-heart surgery.

“With advice from the doctors we sought help from Al Jalila Foundation and were thrilled to receive speedy response approving our request for Zain’s treatment. We were overwhelmed with relief and grateful for the end to our sleepless nights.”

At 10-months, Zain underwent the vital surgery conducted by specialist cardiologists at Al Jalila Children’s Specialty Hospital. Today Zain, almost 2-years-old, is regularly monitored by the medical team and is a happy, healthy toddler with a full life ahead of him.

Cardiovascular disease is the world’s number one cause of death and Zain’s inspiring story is one of hundreds who have overcome heart disease with the support of Al Jalila Foundation.

Scientist studies the effect of carnosol on breast cancer

Celebrated scientist and Al Jalila Foundation research grant recipient, Professor Rabah Iratni from United Arab Emirates University, is studying a naturally occurring polyphenol, carnosol, and its effect on breast cancer.

Breast cancer ranks as the leading cause of cancer death in women worldwide with triple-negative breast cancers (TNBCs) being the most aggressive and invasive form with the worst prognosis. Sadly, TNBCs lack effective treatments with identification of targeted efficient therapies remaining a clinical challenge.

Professor Iratni previously reported that carnosol, a natural compound found in rosemary and sage, induced cell death of the mutant TNBC cells through activation of both autophagic and apoptotic pathways.

This study aims to explain the molecular mechanism through which carnosol exerts its anti-TNBC activity. Based on preliminary results, the team hypothesize that one possible mechanism of action of carnosol on TNBC is through the downregulation of the death-associated protein kinase 1 (DAPK1), a protein recently shown to be essential for the growth TNBCs. The hope is that the findings from this study may reveal a novel therapeutic approach based on small natural molecules targeting DAPK1 in aggressive forms of breast cancer and that carnosol may serve as lead agent for the development of such anti-cancer therapy.

Read more about Professor Iratni’s research here.

Aya pursues a career in medicine

Aya Akhras’ lifelong dream was to help people and while excelling at biology in high school she set her sights on becoming a doctor. Thanks to her exceptional academic record, in 2016, Aya gained admission to the Mohammed Bin Rashid University of Medicine and Healthcare Sciences (MBRU) College of Medicine to pursue a Bachelor of Medicine and Bachelor of Surgery (MBBS) with a scholarship from Al Jalila Foundation.

“The Al Jalila Foundation scholarship and studying at MBRU give me a great sense of accomplishment and I feel honored to be recognised for my efforts while doing what I love.”

Over the past 3 years, Aya has proven herself a worthy candidate for the sought after scholarship and participated in an internship at Queens University in Belfast, a summer research program at Mayo Clinic and an observership at Cleveland Clinic. Aya is also very involved in student life at MBRU and in addition to her rigorous academic schedule Aya is an aspiring baker who sees baking as a way of spreading happiness and connecting people.

Expected to graduate in 2022, Aya believes that the physician of the future is a multi-faceted individual capable of displaying their talents in many ways. “I see myself practicing as a physician, researcher and hopefully obtaining a position in academia, as I am passionate about medical education and educating the physicians of the digital age.”

Khalid’s determination inspires the nation

Khalid Al Ali is a young Emirati man with an enchanting smile and a strong will. The 26-year-old athlete – an international swimmer and a member of the UAE National Swim Team – has a long list of hobbies that include horseback riding, sailing and kayaking.

He has also participated in international sports championships in several countries including representing the UAE in kayaking in the Special Olympics World Games held in Abu Dhabi in 2019.

Born with Down syndrome, Khalid has become an inspiring young man, thanks to his perseverance and his family’s support. His Father enrolled in Al Jalila Foundation’s ‘Ta’alouf’ program, which trained him to communicate better with Khalid and understand his feelings and behaviour, helping the family to further empower him towards fulfilling his potential and meeting his aspirations.

Ta’alouf has empowered hundreds of parents and teachers with each one of them working daily to bring inclusiveness into our community, homes, classrooms and playgrounds so every child has the opportunity to thrive and experience all that life has to offer.

Watch Khalid’s Story of Hope here.